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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANAPC1
All Species:
22.42
Human Site:
T838
Identified Species:
44.85
UniProt:
Q9H1A4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1A4
NP_073153.1
1944
216500
T838
M
H
H
P
S
F
F
T
S
E
P
P
S
I
Y
Chimpanzee
Pan troglodytes
XP_515601
1394
155989
Y345
V
S
D
E
S
S
Q
Y
L
T
R
I
T
I
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532958
1943
216470
T837
M
H
H
P
S
F
F
T
P
E
P
P
S
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
P53995
1944
216068
T838
M
H
H
P
P
F
F
T
S
E
P
P
S
I
Y
Rat
Rattus norvegicus
NP_001101241
1944
216060
T838
M
H
H
P
S
F
F
T
S
E
P
P
S
I
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419303
1945
216100
S839
M
H
H
P
A
F
F
S
A
E
P
P
S
I
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921168
1979
220132
N880
M
T
W
P
V
F
L
N
G
E
A
P
C
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573025
2030
227256
R901
M
L
H
Q
E
L
L
R
V
P
A
P
S
V
F
Honey Bee
Apis mellifera
XP_001122449
1939
218025
S833
I
I
I
P
N
Y
V
S
S
K
P
P
N
V
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202400
910
100394
Poplar Tree
Populus trichocarpa
XP_002312165
1929
212815
L847
T
V
S
D
T
T
G
L
E
S
A
K
F
E
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196175
1678
186257
D629
Y
L
D
Y
Y
I
R
D
F
P
R
L
S
T
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.5
N.A.
97.3
N.A.
92.1
92.9
N.A.
N.A.
81.7
N.A.
66
N.A.
33.6
38
N.A.
25.2
Protein Similarity:
100
71.5
N.A.
98.5
N.A.
96
96.5
N.A.
N.A.
90.2
N.A.
79
N.A.
52.2
59.1
N.A.
33.8
P-Site Identity:
100
13.3
N.A.
93.3
N.A.
93.3
100
N.A.
N.A.
73.3
N.A.
33.3
N.A.
26.6
26.6
N.A.
0
P-Site Similarity:
100
26.6
N.A.
93.3
N.A.
93.3
100
N.A.
N.A.
100
N.A.
46.6
N.A.
40
80
N.A.
0
Percent
Protein Identity:
28.5
N.A.
N.A.
27.2
N.A.
N.A.
Protein Similarity:
47
N.A.
N.A.
45.8
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
9
0
25
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
17
9
0
0
0
9
0
0
0
0
0
0
9
% D
% Glu:
0
0
0
9
9
0
0
0
9
50
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
50
42
0
9
0
0
0
9
0
34
% F
% Gly:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% G
% His:
0
42
50
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
9
9
0
0
9
0
0
0
0
0
9
0
50
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% K
% Leu:
0
17
0
0
0
9
17
9
9
0
0
9
0
0
0
% L
% Met:
59
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
9
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
59
9
0
0
0
9
17
50
67
0
0
0
% P
% Gln:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
9
9
0
0
17
0
0
0
0
% R
% Ser:
0
9
9
0
34
9
0
17
34
9
0
0
59
0
0
% S
% Thr:
9
9
0
0
9
9
0
34
0
9
0
0
9
9
9
% T
% Val:
9
9
0
0
9
0
9
0
9
0
0
0
0
25
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
9
9
9
0
9
0
0
0
0
0
0
34
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _